What is the Endocannabinoid Structure?

The endocannabinoid Structure is complex, primarily consisting of receptors, enzymes, and endocannabinoids. Extensive research was conducted, starting in the ’90s regarding CBD. There are over 100 medicinal benefits. The most known and conclusive are appetite, sleep, mood, and memory. There is much to be discovered about the effects on physical and mental ailments.

What is fascinating, is the fact that our bodies already possess receptors called endocannabinoids (That are within our bodies).  The cannabinoids within CBD connect with the endocannabinoids and do magical things to the body.  There are two types of receptors.  The other fascinating aspect of the endocannabinoid structure is that it exists in animals too.  Endocannabinoid systems have been found in mammals, birds, reptiles, and fish. CBD and cannabis have been part of veterinary medicine for a long time. Ancient Greeks used cannabis to treat horses for colic, and inflammation, and to heal battle wounds.  Walter E. Dixon published research in the British Medical Journal in 1899 related to cannabis and its response in cats and dogs.

Potential benefits include pain management, inflammation reduction, arthritis relief, seizure management, aiding in the loss of appetite, and cancers.   Many endocannabinoid systems in animals are not being activated, because of a lack of endocannabinoids in the food we eat.  Hemp is being taken out of food and there are no CBD medicinal benefits for humans or animals.   Hence the reason for digesting CBD directly into the body of animals and humans daily.

A) CBD1 receptors are expressed throughout the brain, like a circuit breaker that releases inhibitory and excitatory neurotransmitters.  These receptors are abundant in the nervous system, primarily localized in the central and peripheral neurons. CB1
receptors are responsible for the psychoactive effects of cannabis.  The CBD1 receptor exists within the Central Nervous System (Consisting of the areas within the spinal cord and brain) and primarily controls our movement, pain, mood, appetite, and more…
Cannabinoid Receptor 1 or CB1 is associated with psychoactive, neuromodulatory, and analgesic effects due to its activation by a lipid called tetrahydrocannabinol (THC).

B) CB2 Receptors are expressed in the immune cells; including leukocytes (White blood cells), splenocytes (Splenic white blood cells), osteoblasts (Cells that secrete matrix for bone formation), osteoclasts (The bone cell that absorbs bone tissue during growth and
healing).  CB2 receptors help control the release of cytokines linked to inflammation and immune function. Studies have suggested that this receptor may assist in the selection of inputs that guide complex behavior. CBD2 receptors are found within the sense organs or Peripheral Nervous System (Which consists of nerves lying outside of the central nervous system) its primary role is to connect the Central Nervous system with the body’s organs, limbs, and skin.  Phytocannabinoids found in hemp largely activate CB2,
thus exerting positive, non-psychoactive effects on the human body.